The Laboratories in the Children's Hospital Informatics Program span a wide range of research interests in bioinformatics and clinical informatics. Our goal is to make significant contributions to biomedical research and patient care by understanding and utilizing various types of genomic and proteomic data and by developing innovative hardware and software technologies.
Our group studies the application of medical informatics, computer science, epidemiology, and biostatistics to improve public health and clinical practice.
The Computational Epidemiology Group aims to evolve the traditional paradigm of public health practice and surveillance through innovative multi-disciplinary epidemiologic research. The overall goal is to show how emerging technologies can help clarify patterns of disease and promote public health. Our mission has materialized in a diverse set of projects that include describing the emergence of West Nile virus in New York City using satellite data, predicting patterns of Lyme disease based on climate change, analyzing patterns of influenza epidemics, finding new ways to identify problem medications using electronic medical records, understanding the geographic patterns of substance abuse, describing the impact of pollution on chronic disease, and most recently the first documented use of mobile smartphones as public health surveillance tools for both outbreak and post-marketing surveillance.
We are a bioinformatics group interested in understanding chromatin structure and function in a variety of systems using high-throughput sequencing techniques. We specialize in analysis of ChIP-seq and nucleosome profiling data but also work with RNA-seq, whole-genome sequencing, and other data types. We collaborate with a number of experimental labs, both in the Harvard Medical area and around the world.
The Biomedical Cybernetics Laboratory is an interdisciplinary program of the Harvard Medical School - Partners Healthcare Center for Personalized Genetic Medicine, affiliated with the Children's Hospital Informatics Program and the Harvard-MIT Division of Health Sciences and Technology. Our laboratory brings together researchers from computer science, engineering, artificial intelligence, epidemiology and statistics to develop novel methods for the integrated analysis of biomedical systems.